What we passed on, and whether we were right
Every candidate that has left the live board — its catalyst date has passed, or its prediction has settled — together with what became of it. Two questions live here: how many screened candidates turned into a full analysis and how those analyses actually settled, and — the newer one — whether the candidates dismissed along the way were dismissed for good reasons. Scoring a dismissal needs a primary source, so this page never guesses at an outcome; it names the slot and leaves it unrecorded until someone runs the connector call.
NOT CITABLE — screening only
This is a cheap ranked screen, not an analysis. No claim on this board may enter a program
analysis without being re-verified there (framework/02-connectors.md § Triage
pass). It exists to decide what is worth analysing next, not to support a claim on its own.
Archived
10
left the live board
Became an analysis
7
of 10 archived
Dismissed
0
of the archived rows
Settled
6
prediction resolved
Dismissal reasons
Each tag from the closed taxonomy, with its count — the seed of the pattern analysis. Recalibrating the A/B/C/D tiers from this is future work, gated on at least 20 dismissals across 3 screens (ROADMAP.md).
Mislabelled row
0
The row's stage or event label contradicts its own note.
Date conflict
0
catalyst_date_text disagrees with the note's own timing.
Not a binary
0
Interim, additional data, or an endpoint already met.
Financing first
0
Runway ends at or before the event; a raise comes first.
Diluted materiality
0
Partner-run, multi-asset or revenue-generating, so one readout cannot move it.
Duplicate exposure
0
The same event is already reachable through another row.
Already priced
0
The run-up is spent, or a larger event lands first.
Uninvestable
0
Share count, liquidity or capitalisation makes the equity untradeable regardless of the data.
Outside window
0
The real event falls before or after the screened window.
Base rate
0
Indication base rate or a failed sister trial argues against it.
Other
0
Anything else. The note carries the whole argument.
No dismissal has reached this page yet — a dismissed row only arrives here once its catalyst date
passes or its prediction settles (see /triage for dismissals still live). The taxonomy
above is the full set from framework/02-connectors.md § Triage pass; counts fill in as
screens turn into decisions and those decisions age past their event.
Archived candidates
What became of every row that left the live board
| Tier | Ticker | Drug | Indication | Catalyst | Why archived | Dismissal | Became |
|---|---|---|---|---|---|---|---|
| C | RARE | GTX-102 | Angelman syndrome (ASPIRE) | H2 2026 | prediction settled | — | Analysed
view analysis →
Settled — miss — ASPIRE missed its primary (Bayley-4 cognitive raw score) and key secondary (MDRI) endpoints vs sham (-42.4%) |
| A | TYRA | Dabogratinib (TYRA-300) | Low-grade, intermediate risk non-muscle invasive bladder cancer (IR NMIBC) | September 2026 | prediction settled | — | Analysed
view analysis →
Settled — miss — pooled 3-month CR 46% (12/26) vs the ≥60% bar; safety clean (-17.75%) |
| A | EVMN | EVO756 (MRGPRX2 Antagonist) | Moderate-To-Severe Atopic Dermatitis | Q3 2026 | prediction settled | — | Analysed
view analysis →
Settled — miss — primary endpoint (% change in EASI at Week 12) not met at any dose; EVO756 not advanced in AD (-15.58%) |
| A | IRON | DISC-3405 (formerly MWTX-003) | Polycythemia vera | Q3 2026 | prediction settled | — | Analysed
view analysis →
Settled — positive — 61.5% phlebotomy-free through 26 weeks (Cohort A, n=13), phlebotomies 4.0→0.6 (p<0.0001), well tolerated, advancing (-5.97%) |
| A | CNTB | Rademikibart /CBP-201 | Asthma (Seabreeze STAT) | Early September 2026 | catalyst date passed | — | Analysed
view analysis →
Settled — miss — primary 28-day treatment failure not significant (p=0.153); FEV1 key secondary met (p=0.023) (-36%) |
| A | LGVN | Lomecel-B (laromestrocel) | Hypoplastic Left Heart Syndrome | August 2026 | catalyst date passed | — | Analysed
view analysis →
Settled — miss — RVEF primary not met (p=0.8336); MACE and clinical composite not significant (-61.6%) |
| C | BIVI | Bezisterim (NE3107) | Neurological symptoms associated with long COVID | Late Summer 2026 | catalyst date passed | — | Screened |
| C | OSTX | OST-HER2 | Pediatric lung metastatic osteosarcoma | Summer 2026 | catalyst date passed | — | Screened |
| A | VALN | Shigella4V2 (S4V2) | Prevention of shigellosis | Mid-2026 | catalyst date passed | — | |
| B | CNSY | REYOBIQ (Rhenium Re186 Obisbemeda) | Leptomeningeal Metastases (LM) | August 13, 2026 | catalyst date passed | — | Screened |